Para peneliti juga menemukan bahwa makin besar ukuran hiu, makin tinggi pula kadar timbal yang terakumulasi.
Timbal sangat berbahaya bagi manusia. Paparannya dapat menyebabkan keluhan ringan seperti sakit perut dan sakit kepala, hingga masalah serius seperti kejang, koma, bahkan kematian. Mengonsumsi daging hiu, terutama dari spesies besar, hiu yang lebih tua, atau bagian organ dalam, dapat meningkatkan risiko keracunan timbal.
Dengan semua risiko dari logam berat seperti merkuri, arsenik, dan timbal, hingga racun biologis dan kontaminasi mikroba, daging hiu bukan pilihan yang aman untuk dikonsumsi. Bahayanya bukan cuma zat beracun yang terakumulasi secara alami dalam tubuh hiu, tetapi juga bagaimana hiu ditangani setelah ditangkap. Tanpa pengolahan yang tepat, risiko keracunan akan meningkat drastis dan dampaknya pada kesehatan pun tak main-main.
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